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A Team of researchers in Singapore have announced that it may one day be feasible to identify patients who are at high risk of developing glaucoma and keratoconus based on just their genetic profile.
Blinding conditions such as glaucoma have been associated with particular genes that develop the central corneal thickness.
With an estimated heritability of up to 95%, CCT may determine the severity of one’s glaucoma and assist ODs in identifying patients with high risk for progression.
The study is huge, incorporating just under sixty hospitals and research centres worlwide. Meta -Analaysis on data from more than twenty thousand european and asian subjects was used. The research identified a total of 26 Central Corneal Thickness - associated genetic loci including a number for keratoconus, a condition for which genes were not forthcoming prior to this extensive study.